HCMC RESOURCES

Laws, Regulations, Policy Changes & Research

A curated library of regulatory authority, policy updates, and peer-reviewed publications relevant to medical device and biologics distribution, wound care, and advanced tissue therapeutics. Reviewed periodically as policy and literature evolve.

Important Legal Notice

This page is a convenience — not advice or endorsement

This page links to publicly available government, regulatory, industry-association, and peer-reviewed sources. HCMC is not the author or publisher of any linked material, is not affiliated with or endorsed by any government agency or third-party organization, and makes no representation that linked information is current, complete, accurate, or applicable to any specific clinical, reimbursement, or business situation.

This page is not legal, clinical, reimbursement, or insurance advice. Consult your own qualified counsel, treating clinician, payer, and insurance carrier for guidance specific to your circumstances. You are responsible for verifying you are accessing the current version of any information before relying on it — external content can change without notice.

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Laws & Regulations Federal

FDA Overview of Medical Device Regulation

Comprehensive regulatory framework for medical devices, including 510(k), PMA, and De Novo pathways, classification, labeling, and post-market obligations.

FDA.gov
Laws & Regulations Federal

21 CFR Part 1271 — HCT/P Regulations

The FDA regulation governing Human Cells, Tissues, and Cellular & Tissue-Based Products — the framework underlying 361 HCT/P registration vs. 351 biologic classification.

eCFR
Laws & Regulations Federal

OIG Anti-Kickback & Stark Compliance Guidance

Office of Inspector General guidance on Anti-Kickback Statute (AKS) safe harbors, Stark Law physician self-referral rules, and fraud-and-abuse enforcement priorities for the medical-device industry.

HHS OIG
Laws & Regulations Federal

FTC CAN-SPAM Business Compliance Guide

Required elements for every commercial email: accurate sender identity, clear opt-out mechanism, physical postal address, honored unsubscribe requests within 10 business days.

FTC.gov
Laws & Regulations Federal

HHS HIPAA Privacy & Security Rules

The Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule and Security Rule — applies when handling Protected Health Information (PHI). Business Associate Agreement (BAA) requirements included.

HHS.gov
CMS & Reimbursement Federal

CMS Medicare Coverage Database

National Coverage Determinations (NCDs), Local Coverage Determinations (LCDs), and coverage articles — the authoritative source for Medicare Part B coverage of devices, biologics, and clinical procedures.

CMS.gov
CMS & Reimbursement Federal

CMS Medicare Fee Schedules

Physician Fee Schedule (MPFS), Ambulatory Surgical Center (ASC) payment system, Hospital Outpatient Prospective Payment System (OPPS), and DMEPOS fee schedules — including annual updates and coding changes. HCMC does not publish, endorse, or guarantee any fee-schedule figure; verify directly with CMS and your payer.

CMS.gov
CMS & Reimbursement Federal

HCPCS Level II Coding Updates

Healthcare Common Procedure Coding System — quarterly HCPCS updates governing how devices, biologics, and supplies are billed to Medicare and most other payers.

CMS.gov
CMS & Reimbursement Federal

2026 OPPS Final Rule — CTP Flat Rate

The CY 2026 Hospital Outpatient Prospective Payment System (OPPS) Final Rule and its implementation of a flat per-square-centimeter payment for Cellular and Tissue-based Products (CTPs) — a material reimbursement change for wound care distributors.

CMS.gov
Research & Guidance Peer-Reviewed

PubMed — NIH/NLM

The National Library of Medicine's bibliographic database of biomedical literature — the primary index for peer-reviewed publications cited in any HCMC product or clinical content.

NIH/NLM
Research & Guidance Federal

ClinicalTrials.gov

NIH registry and results database of publicly and privately supported clinical studies — the source to verify a trial's status, eligibility, endpoints, and investigators when reviewing claims based on registered research.

NIH/NLM
Research & Guidance Federal

FDA Guidance Documents

FDA's publicly available guidance for industry — searchable by product area, document type (draft/final), and date. The authoritative source for FDA's current thinking on regulatory interpretation and expectations.

FDA.gov
Research & Guidance Preprint

bioRxiv & medRxiv

Preprint servers for life-science and health-science research. Valuable for tracking emerging science, but preprints are not peer-reviewed — verify publication in a peer-reviewed journal before relying on findings.

Cold Spring Harbor
Research & Guidance Federal

HHS Office of Research Integrity — Case Summaries

The federal authority on research misconduct for HHS-funded work. Publishes findings on individual researchers, administrative actions, and debarment notices. Authoritative for any citation tied to NIH-funded research.

HHS ORI
Research & Guidance Federal

PubMed Retracted Publication Filter

NIH/NLM's authoritative index of papers officially tagged as retracted. Direct lookup to verify a cited article has not been withdrawn. Use this first for any evidence check; federal sources carry more weight than private databases.

NIH/NLM
Research & Guidance Federal

FDA Warning Letters Database

Public archive of FDA enforcement correspondence. Searchable by product, company, and area. Useful for confirming whether a manufacturer, product, or claim has been the subject of prior enforcement action — a critical check before citing competitor evidence.

FDA.gov
Research & Guidance Industry

Retraction Watch & COPE

The Committee on Publication Ethics (COPE) and Retraction Watch database — independent, non-profit sources tracking retractions and publishing-integrity concerns. Used alongside federal sources because they cover investigations in progress and non-HHS-funded work that the federal system does not reach.

Retraction Watch / COPE
Organizations Industry

AdvaMed Code of Ethics

The voluntary industry code governing medical-device company interactions with U.S. healthcare professionals — gifts, meals, research grants, speaker payments, consulting arrangements. Adherence is industry-standard.

AdvaMed
Organizations Federal

NPI Registry (NPPES)

The CMS National Plan and Provider Enumeration System — public lookup for any U.S. healthcare provider's National Provider Identifier, taxonomy, and practice location. Useful for verification before outreach or contracts.

CMS.gov
Organizations Federal

VA Federal Supply Schedule

The Department of Veterans Affairs Federal Supply Schedule program — the primary procurement pathway for medical devices, biologics, and pharmacy products purchased by VA Medical Centers and other federal healthcare facilities.

VA.gov
Organizations Federal

Deployed Medicine — JTS / CoTCCC

The Joint Trauma System and Committee on Tactical Combat Casualty Care portal — current TCCC guidelines, clinical practice guidelines, and deployed-medicine education. The authoritative source for combat-medicine doctrine.

DoD JTS